Instituto Politécnico de Lisboa

Edna Ribeiro

Professora Adjunta

Nota Biográfica

Academic Degrees

2014 - PhD Degree in Biology “Low-dose effects of Bisphenol A on human primary vascular endothelial cells and colon cancer cells”  

2008 - Master Degree in Developmental Biology “ Organização da cromatina em estadios iniciais de desenvolvimento de Arabidopsis thaliana

2004 - Bachelor Degree in Clinical Analysis and Public Health

Research Centers 

2015 - Centro de Investigação em Agronomia, Alimentos, Ambiente e Paisagem (LEAF - Linking Landscape, Environment, Agriculture and Food) do Instituto Superior de Agronomia, Universidade de Lisboa

2010-2014 - Centro de Botânica Aplicada á Agricultura (CBAA) do Instituto Superior de Agronomia, Universidade de Lisboa

Cargos

  • Since 2015 - Adjunt Professor at ESTeSL. Teaching in the field of Clinical Analysis and Public Health, particulary in the areas of Microbiology, Parasitology and Hematology.
  • 2009-2014 - PhD Student
  • 2003-2009 - Clinical Analysis and Public Health Technician.

Áreas de Investigação

 Research in the field of occupational and environmental exposures to endocrine disruptors (Bisphenol A). This project aims to assess the effective exposures BPA, to create occupational standards and take effective preventive measures to protect individuals from the potential adverse effects of BPA to human health in the context of risk assessment.

 Research in the field of hemoglobinopathies with the aim to evaluate the potential of naturally occurring compounds with high biological activity, namely Genistein (GN) and Epigallocatechin-3-gallate (EGCG) in the induction of γ-globin gene reactivation and HbF expression and assess potentially associated signaling pathways and epigenetic mechanisms. 

Books:
Edna Ribeiro. Low-dose effects of Bisphenol A on human primary and cancer cells. LAP LAMBERT Academic Publishing EAN:9783659827761    Peer-reviewed Papers:

Edna Ribeiro-Varandas, H Sofia Pereira, Wanda Viegas, Margarida Delgado. 2015 Bisphenol A alters transcript levels of biomarker genes for Major Depressive Disorder in Vascular Endothelial Cells and Colon Cancer Cells. Accepted in Chemosphere ID:CHEM36227.

Margarida Delgado and Edna Ribeiro-Varandas. 2015. Bisphenol A at the reference level counteracts doxorubicin transcriptional effects on cancer related genes in HT29 cells. Toxicol In Vitro, Dec;29(8):2009-14

Ribeiro-Varandas E, Ressureição F, Viegas W, Delgado M. 2014. Cytotoxicity of Eupatorium cannabinum L. extract against colon cancer cells and interactions with Bisphenol A and Doxorubicin. BMC Complementary and Alternative Medicine. 14:264

Ribeiro-Varandas E, Pereira HS, Monteiro S, Ferreira RB, Neves E., Brito L, Viegas W, Delgado  M. 2014. Bisphenol A disrupts transcription and decreases viability in aging vascular endothelial cells. International Journal of Molecular Sciences.15:15791-15805

Ribeiro-Varandas E, Viegas W, H Sofia Pereira, Delgado M. 2013. Bisphenol A at concentrations found in human serum induces aneugenic effects in endothelial cells. Mutation Research. 751: 27-33.

Delgado M, Frescatada M, Ribeiro-Varandas E, Viegas W, Neil Jones R. 2010. Dynamics of Functional Heterochromatic Domains in the Plant Interphase Nucleus. Citogenetic and Genome Research 129:64-71

A. Carvalho, Delgado M, Barão A, Frescatada M, Ribeiro E, Pikaard C, Viegas W, Neves N. Chromossome and DNA methylation dynamics during meiosis in the autotetraploid Arabidopsis arenosa. Sex Plant Reprod (2010) 23:29-37

Edna Ribeiro-Varandas, H Sofia Pereira, Sara Monteiro, Ricardo Boavida Ferreira, Elsa Neves, Luisa Brito, Wanda Viegas, Margarida Delgado. 2012. "The Environmental Pollutant Bisphenol A Interferes with Nucleolar Structure", 2012 International Conference on Biomedical Engineering and Biotechnology, icbeb, pp.1811-1814

Ribeiro-Varandas E, Pereira HS, Monteiro S, Ferreira RB, Neves E., Brito L, Viegas W, Delgado  M. 2014. Bisphenol A disrupts transcription and decreases viability in aging vascular endothelial cells.  Global Medical Dicovery,Key Scientific Articles.  

Selected conferences participation:

Oral Comunications:

Ribeiro-Varandas E, H. Sofia Pereira, Viegas W, Delgado M. 2015 “Bisphenol A alters transcript levels of biomarker genes for Major Depressive Disorder in Vascular Endothelial Cells and Colon Cancer Cells” II International Health Congress Gaia-Porto 19-21 November, Porto, Portugal.

Ribeiro-Varandas E. 2015 Workshop: O paradigmático Bisfenol A. VII Encontro Nacional das Ciencias e Tecnologias da Saúde. 12-14 November, Lisbon Portugal.

Ribeiro-Varandas E. 2015 Erasmus day: “Unraveling effects of the xenoestrogen Bisphenol A” 20 May, Lisbon Portugal.

Ribeiro-Varandas E, Viegas W, Delgado M. 2013 “Bisphenol A antagonizes Doxorubicin effects on expression patterns of cancer related genes in colon cancer cells HT29”. 2nd International Conference on Occupational and Environmental Toxicology, 16-18 September, Porto, Portugal.

Ribeiro-Varandas E.,Viegas W.,Delgado M. 2011 “Bisphenol A affects mitosis at physiological concentrations.” XXXVI Jornadas Portuguesas de Genética; 30 de Maio a 1 Junho, Coimbra.

Chromatin club presentation "Unraveling effects of the xenoestrogen Bisphenol A on chromatin " Dezembro 2011

Ribeiro-Varandas E., Carvalho A., Barão A., Pereira H.S., Viegas W.,Delgado M. 2010 “Heterochromatin and methylation dynamics during embryogenesis and early germination in Arabidopsis thaliana.” XXXV Jornadas Portuguesas de Genética, 31 de Maio a 2 Junho, Braga.

Ribeiro E. 2005. “Doseamento do Péptido Natriurético Tipo B em Patologias cardiovasculares e Respiratórias”, II Congresso do Departamento das Ciências e Tecnologias Laboratoriais e Intervenção Comunitária, Escola Superior de Tecnologias da Saúde de Lisboa, 16-20 de Maio, Lisboa.

Poster Comunications:

Ribeiro-Varandas E, H. Sofia Pereira, Viegas W, Delgado M. 2015. Efeitos do xenoestrógeneo Bisfenol A no envelhecimento celular. VII Encontro Nacional das Ciencias e Tecnologias da Saúde. 12-14 Novembro, Lisbon Portugal.

Ana Sofia Tavares, Ana Almeida, Cátia Monteiro, Céu Leitão, Edna Varandas, Inês Lopes, Fernando Bellém, Renato Abreu. 2015. The efficiency of urine dipsticks for the diagnosis of Urinary Tract Infection. VII Encontro Nacional das Ciencias e Tecnologias da Saúde. 12-14 Novembro, Lisbon Portugal

Ribeiro-Varandas E., Viegas W., Delgado M. 2010. BPA induces epigenetic modifications in HUVEC and HT-29 human cell lines. Epigenetics and Stem Cells Conference August 25-27, Copenhagen, Denmark.

Edna Ribeiro, Augusta Barão, Wanda Viegas, Margarida Delgado, 2009. DNA methylation dynamics of pericentromeric and centromeric chromatin during Arabidopsis species development. 8th PlantGEM, October 2009, Lisbon, Portugal.

Edna Ribeiro, Augusta Barão, Ana Luísa Carvalho, Wanda Viegas, Margarida Delgado, 2008. Heterochromatin dynamics during seed germination in Arabidopsis thaliana. XVI National Congress of Biochemistry, October 2008, Ponta Delgada-Açores, Portugal.

Projects:

PTDC/AAC-AMB/103968/2008 “Avaliação de efeitos epigenéticos de EDCs utilizado como modelo C. elegans.” – Maria Margarida Delgado - Centro de Botânica Aplicada á Agricultura.

PPCDT/BIA-BCM/59389/2004 "Estudo da dinâmica da heterocromatina durante o desenvolvimento de Arabidopsis: efeitos de enzimas remodeladoras da cromatina e modificações epigenéticas" Coordenador - Nuno Alberto Ferreira Neves Unidade de Investigação - Centro de Botânica Aplicada á Agricultura.